Chordin (CHRD) (Center) Rabbit Polyclonal Antibody

CAT#: AP50905PU-N

Chordin (CHRD) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis in mouse cerebellum tissue lysates (35ug/lane) using Chordin antibody. This demonstrates the CHRD antibody detected the CHRD protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  Western blot: 1/100-1/500.
  Enzyme immunoassay: 1/1000.

• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: Synthetic peptide - KLH conjugated - corresponding to the central region (between 438-467aa) of human Chordin
• Specificity: This antibody recognizes Chordin.
• Formulation: PBS with 0.09% (W/V) Sodium azide
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Purified through a Protein A column followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens chordin (CHRD), transcript variant 1
• Database Link:
  Entrez Gene 8646 Human
  UniProt ID Q9H2X0
• Background: The CHRD gene encodes a secreted protein, Chordin that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins and sequestering them in latent complexes. Chordin may also have roles in organogenesis and during adulthood. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequence has not been determined.
• Synonyms: CHRD
• Note: Molecular Weight: 102032 Da

Reference Data

• Protein Families: Secreted Protein
• Protein Pathways: TGF-beta signaling pathway