ALOXE3 (Center) Rabbit Polyclonal Antibody

CAT#: AP50154PU-N

ALOXE3 (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

ALOXE3 Antibody (Center) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the ALOXE3 antibody detected the ALOXE3 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western blotting: 1/100 - 1/500.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 230-260 amino acids from the Central region of human ALOXE3
• Specificity: This antibody reacts to ALOXE3.
• Formulation: PBS containing 0.09% (W/V) sodium azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: arachidonate lipoxygenase 3
• Database Link:
  Entrez Gene 23801 MouseEntrez Gene 59344 Human
  UniProt ID Q9BYJ1
• Background: ALOXE3 is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin.
• Synonyms: e-LOX-3, eLOX3, Epidermis-type lipoxygenase 3
• Note: Molecular Weight: 80543 Da

Reference Data

• Protein Families: Druggable Genome