PLA2G5 (C-term) Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | ELISA, WB |
Recommended Dilution | ELISA. |
Reactivities | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide derived from C terminal part of Human PLA2G5 protein. |
Specificity | This antibody reacts with the 16 kDa Human PLA2G5 protein. |
Formulation | 0.1M Tris, 0.1M Glycine, 2% Sucrose State: Purified State: Lyophilized powder Preservative: None |
Reconstitution Method | Restore in distilled water |
Purification | Protein A Chromatography |
Conjugation | Unconjugated |
Storage | Lyophilized powder stable for a minimum of 2 years at -20°C. |
Stability | Shelf life: Six months from despatch. |
Gene Name | phospholipase A2 group V |
Database Link | |
Background | Secretory phospholipase A2 Type V (PLA2) catalyzes the hydrolysis of fatty acids at the sn-2 position of glycerophospholipids and is one of the isoforms in the growing list of the PLA2 enzyme family. This enzyme, rather than sPLA2 (Type II), is responsible for arachidonic acid mobilization leading to prostaglandin production in macrophages and mast cells. Consistent with this role, sPLA2 (Type V) is associated with the golgi apparatus, nuclear envelope, and plasma membrane in murine bone marrow-derived mast cells. sPLA2 (Type V) has been cloned from a variety of species including human, mouse and rat. The enzyme is expressed in heart, lung, placenta and spleen, as well as P388D1 macrophages and mast cells. |
Synonyms | Phosphatidylcholine 2-acylhydrolase, PLA2-10, Group V phospholipase A2 |
Reference Data |
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