KCNN4 (N-term) Rabbit Polyclonal Antibody

CAT#: AP23278PU-N

KCNN4 (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

KCNN4 (KCA3.1) Polyclonal Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: At 0.5-1μg/ml with the appropriate system to detect KCNN4 in cells and tissues.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a sequence mapping at the C-terminal of human KCNN4
• Specificity: This antibody detects KCNN4 at N-term. No cross reactivity with other proteins.
• Formulation: 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3
  State: Aff - Purified
  State: Lyophilized Ig fraction
• Reconstitution Method: 0.2ml of distilled water will yield a concentration of 500μg/ml.
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: potassium calcium-activated channel subfamily N member 4
• Database Link:
  Entrez Gene 16534 MouseEntrez Gene 65206 RatEntrez Gene 3783 Human
  UniProt ID O15554
• Background: Intermediate conductance calcium-activated potassium channel protein 1 (KCNN4,Kca3.1) is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. KCNN4 may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily.
• Synonyms: KCNN4, IK1, IKCA1, KCA4, SK4, KCa3.1, Putative Gardos channel

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Potassium, Transmembrane