Superoxide Dismutase 3 (SOD3) (N-term) Rabbit Polyclonal Antibody

CAT#: AP17757PU-N

Superoxide Dismutase 3 (SOD3) (N-term) rabbit polyclonal antibody

Product Images

Western blot analysis of SOD3 Antibody (N-term) in K562 cell line lysates (35ug/lane). SOD3 (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/50 - 1/100.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the N-terminal region of human SOD3
• Specificity: This antibody reacts to SOD3.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: superoxide dismutase 3, extracellular
• Database Link:
  Entrez Gene 6649 Human
  UniProt ID P08294
• Background: SOD3 is a member of the superoxide dismutase(SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. This protein is thought to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix (ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM.
• Synonyms: SOD-3, EC-SOD, Extracellular superoxide dismutase [Cu-Zn]

Reference Data

• Protein Families: Druggable Genome, Secreted Protein