FUCA1 Rabbit Polyclonal Antibody

CAT#: AP17405PU-N

FUCA1 rabbit polyclonal antibody

Product Images

Western blot analysis of FUCA1 Antibody (Center) in HepG2 cell line lysates (35 ug/lane). FUCA1 (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1:50 - 1:100.
  ELISA: 1:1,000.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the Center region of human FUCA1
• Specificity: This antibody detects FUCA1 at Center.
• Formulation: PBS with 0.31% (W/V) sodium azide
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: fucosidase, alpha-L- 1, tissue
• Database Link:
  Entrez Gene 2517 Human
  UniProt ID P04066
• Background: FUCA1 is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids. Mutations in this gene are associated with fucosidosis (FUCA1D), which is an autosomal recessive lysosomal storage disease. A pseudogene of this locus is present on chr 2.
• Synonyms: Nbla10230
• Note: Molecular weight: 53689 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Lysosome, Other glycan degradation