APPBP1 (NAE1) (C-term) Rabbit Polyclonal Antibody

CAT#: AP13996PU-N

APPBP1 (NAE1) (C-term) rabbit polyclonal antibody, Purified


USD 560.00

2 Weeks*

Size
    • 400 ul

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Specifications

Product Data
Applications IHC, WB
Recommended Dilution ELISA: 1/1,000.
Western blot: 1/1000.
Immunohistochemsitry: 1/10-1/50.
Reactivities Human
Host Rabbit
Isotype Ig
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide between 452-482 amino acids from the C-terminal region of human NAE1 (APPBP1).
Specificity This antibody detects NAE1 (APPBP1) at C-term.
Formulation PBS with 0.09% (W/V) sodium azide
State: Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Conjugation Unconjugated
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name NEDD8 activating enzyme E1 subunit 1
Background APPBP1 binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, this protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. APPBP1 is required for cell cycle progression through the S/M checkpoint.
Synonyms NAE1, HPP1
Note Molecular weight: 60252 Da
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.