DCAMKL1 (DCLK1) (N-term) Rabbit Polyclonal Antibody

CAT#: AP13897PU-N

DCAMKL1 (DCLK1) (N-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of DCAMKL1 Antibody (N-term) in mouse brain tissue lysate. DCAMKL1 (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA 1:1,000.
  Western blot 1:100 - 1:500.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human DCAMKL1.
• Specificity: This antibody detects DCAMKL1 at N-term.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: doublecortin like kinase 1
• Database Link:
  Entrez Gene 9201 Human
  UniProt ID O15075
• Background: Doublecortin-like kinase (DCAMKL1)(Ser/Thr protein kinase family) is essential for proper neurogenesis, neuronal migration, and axonal wiring. DCAMKL1 is involved in a calcium-signaling pathway controling neuronal migration in the developing brain, and participates in functions of the mature nervous system. DCAMKL1 protein shares high homology with doublecortin (DCX). DCLK, but not DCX, is highly expressed in regions of active neurogenesis in the neocortex and cerebellum. DCAMKL1 controls mitotic division by regulating spindle formation and also determines the fate of neural progenitors during cortical neurogenesis.
• Synonyms: DCLK, DCKL1, DCAMKL1, DCDC3A, CLICK1, KIAA0369
• Note: Molecular weight: 82223 Da