EXOSC8 (C-term) Rabbit Polyclonal Antibody

CAT#: AP12431PU-N

EXOSC8 (C-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of anti-EXOSC8 Antibody (C-term) in HL60 cell line lysates (35ug/lane). EXOSC8 (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western Blot: 1/50-1/100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human EXOSC8.
• Specificity: This antibody detects EXOSC8 (C-term).
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative.
  State: Purified
  State: Liquid purified Ig fraction.
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: exosome component 8
• Database Link:
  Entrez Gene 11340 Human
  UniProt ID Q96B26
• Background: EXOSC8 is a component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3'-untranslated regions. It is required for the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA and has a 3'-5' exonuclease activity.
• Synonyms: OIP2, RRP43,Exosome component 8, p9, Opa-interacting protein 2
• Note: Molecular weight: 29909 Da predicted from amino acid sequence.
  Theoretical pI: 5.17