BMPR1A (Center) Rabbit Polyclonal Antibody

CAT#: AP11858PU-N

BMPR1A (Center) rabbit polyclonal antibody, Purified


USD 574.00

2 Weeks*

Size
    • 200 ul

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Specifications

Product Data
Applications IHC, WB
Recommended Dilution ELISA 1:1,000.
Western blot 1:100 - 1:500.
Immunohistochemistry 1:50 - 1:100.
Reactivities Human, Mouse
Host Rabbit
Isotype Ig
Clonality Polyclonal
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the central region of human BMPR1A.
Specificity This antibody detects BMPR1A.
Formulation PBS with 0.09% (W/V) sodium azide
State: Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Conjugation Unconjugated
Storage Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name bone morphogenetic protein receptor type 1A
Background The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
Synonyms ACVRLK3, ALK3, ALK-3, SKR5
Note Molecular weight: 60198 Da
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.