ENPP1 (915-925) Goat Polyclonal Antibody

CAT#: AP08594PU-N

ENPP1 (915-925) goat polyclonal antibody, Aff - Purified

Product Images

Formalin-Fixed Paraffin-Embedded Human Liver stained with anti-ENPP1 Antibody at 5 ug/ml after heat-induced antigen retrieval.

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  Formalin-Fixed Paraffin-Embedded Human Pancreas stained with anti-ENPP1 Antibody at 5 ug/ml after heat-induced antigen retrieval.

Specifications

Product Data

• Applications: ELISA, IHC
• Recommended Dilution: ELISA: 1/32000.
  Immunohistochemistry on Paraffin Sections: 2.5 - 5 µg/ml.
• Reactivities: Human, Mouse, Rat, Rabbit
• Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from C-terminus of Human ENPP1, aa 915-925 (NP_006199.2)
  
• Specificity: Specific to Human ENPP1 (C-term).
• Formulation: Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: ectonucleotide pyrophosphatase/phosphodiesterase 1
• Database Link:
  Entrez Gene 5167 Human
  UniProt ID P22413
• Background: ENPP1 has a broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. It can hydrolyze nucleoside 5' triphosphates such as ATP, GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate. It can also hydrolyze diadenosine polyphosphates and 3',5'-cAMP to AMP. It may play a role in the regulation of pyrophosphate production, the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling.
• Synonyms: ENPP-1, M6S1, NPPS, PC1, PDNP1, E-NPP 1