ZMYM2 (1250-1300) Rabbit Polyclonal Antibody

CAT#: AP08258PU-N

ZMYM2 (1250-1300) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of Zinc Finger Protein 198 in a mouse skeletal muscle lysate in the absence (Lane 1) and presence (Lane 2) of immunizing peptide using antibody at 0.1 ug/ml.

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  Breast: Formalin-Fixed Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 10 µg/ml.
  Western Blot: 0.1 - 1 µg/ml.
• Reactivities: Bovine, Canine, Chicken, Human, Monkey, Mouse, Rat, Orang-Utan
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to the amino acids 1250-1300 of human Zinc finger protein 198
• Specificity: This antibody recognizes Zinc Finger Protein 198 (ZNF198) (ZMYM2) at aa 1250-1300.
• Formulation: PBS containing 0.05% Sodium Azide as preservative and 0.2% Gelatin as stabilizer
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: zinc finger MYM-type containing 2
• Database Link:
  Entrez Gene 7750 Human
  UniProt ID Q9UBW7
• Background: Zfp198 (zinc finger protein 198, also known as ZNF198 or Zinc finger MYM-type protein 2) is a transcription factor that contains 9 MYM-type zinc fingers. Zfp198 interacts with, and is modified by, SUMO1 and colocalises with PML to nuclear bodies. Zfp198 has also been shown to stabilise the LSD1-CoREST-HDAC1 complex on chromatin through its MYM-type zinc fingers. A chromosomal translocation resulting in a Zfp198-FGFR1 fusion is associated with stem cell leukemia lymphoma syndrome (SCLL). SCLL usually presents as a lymphoblastic lymphoma in association with a myeloproliferative disorder.
• Synonyms: ZNF198, FIM, RAMP