Myelin Basic Protein (MBP) Rabbit Polyclonal Antibody

CAT#: AP08127PU-N

Myelin Basic Protein (MBP) rabbit polyclonal antibody, Purified

Specifications

Product Data

• Applications: IF, IHC
• Recommended Dilution: Suitable for Immunohistochemistry and Immunocytochemistry (Frozen or Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections and cell smears): 1/50-1/100 using streptavidin~biotin system or polymer system.
  Immunofluorescence.
  Recommended positive control: Human brain.
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Purified human MBP.
• Specificity: This antibody stains white matter and oligodendrocyte.
  Cellular Localization: Cytoplasmic.
• Formulation: PBS, pH 7.4 containing 0.05% Sodium Azide as preservative and 1% BSA as stabilizer.
  State: Purified
  State: Liquid purified Ig fraction.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.
• Database Link:
  Entrez Gene 4155 Human
  UniProt ID P02686
• Background: Myelin Basic Protein (MBP) a 19.6 kDa highly basic protein is a major constituent of central nervous system (CNS). This protein is synthesized by oligodendrocyte and Schwann cells. MBP, Proteolipid (PLP), myelin oligodendrocyte glycoprotein (MOG) are primary encephaltogenic target antigens in multiple sclerosis. The gene for MBP is on chromosome 18; the protein localizes to CNS and to various cells of the hematopoietic system. MBP is expressed in oligodendrocyte, myelin of white matter, spinal cord and in peripheral nerves
• Synonyms: MBP