NMDAR1 (GRIN1) Rabbit Polyclonal Antibody

CAT#: AP08051PU-N

NMDAR1 (GRIN1) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of extracts from PC12 and C6 cells using NMDAR1 antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1/500-1/1000.
  Incubate membrane with diluted antibody in 5% nonfat milk, 1xTBS, 0.1% Tween-20 at 4°C with gentle shaking overnight.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Peptide sequence around amino acids 894~898 (R-R-SP-S-K) derived from Human NMDAR1.
• Specificity: This antibody detects endogenous levels of total NMDAR1 protein.
• Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide and 50% Glycerol.
  State: Aff - Purified
  State: Liquid purified Ig fraction.
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store the antibody (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.
• Gene Name: glutamate ionotropic receptor NMDA type subunit 1
• Database Link:
  Entrez Gene 2902 Human
  UniProt ID Q05586
• Background: NMDA receptor subtypes of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. NMDAR1 plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission and is involved in the cell surface targeting of NMDA receptors.
• Synonyms: NMDAR1,GRIN1
• Note: Molecular Weight: 120 kDa