gamma Synuclein (SNCG) Rabbit Polyclonal Antibody

CAT#: AP06417PU-N

gamma Synuclein (SNCG) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of Synuclein ? antibody in extracts from HT29 cells.

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  Immunohistochemistry (IHC) analyzes of Synuclein ? antibody in paraffin-embedded human lung carcinoma tissue.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western blot: 1/500-1/1000.
  Immunohistochemistry on paraffin sections: 1/50-1/200.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 81-130 of Human Synoretin.
• Specificity: This antibody detects endogenous levels of Synuclein γ protein.
  (region surrounding Ala111)
• Formulation: Phosphate buffered saline (PBS), pH 7.2.
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.05% sodium azide
• Concentration: 1.0 mg/ml
• Purification: Affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 20 kDa
• Gene Name: synuclein gamma
• Database Link:
  Entrez Gene 6623 Human
  UniProt ID O76070
• Background: The synucleins, including alpha-synuclein (also designated NACP for nonamyloid component precursor), beta-synuclein (also designated PNP 14 for phosphoneuroprotein 14), and gamma-synuclein (also designated persyn or BCSG1 for breast cancer-specific gene 1) are presynaptic proteins abundant in neurons. alpha-Synuclein, identified as a component of Alzheimers disease amyloid plaques, is localized to neuronal cell bodies and synapses. Coordinate expression of alpha-synuclein and beta-synuclein may be important during hematopoetic cell differentiation. A mutant form of alpha-synuclein is found in patients with early onset Parkinsons disease. gamma-Synuclein is associated with axonal pathology in Parkinsons disease.
• Synonyms: PERSYN, Synuclein gamma, Synoretin, BCSG1, PRSN