Endostatin (COL18A1) Rabbit Polyclonal Antibody

CAT#: AP06103PU-N

Endostatin (COL18A1) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of COL18A1 antibody at 1/500 dilution Lane 1:MCF-7 whole cell lysate Lane 2:PC12 whole cell lysate

• 

  Immunohistochemical (IHC) analysis in paraffin-embedded human lung carcinoma tissue using Collagen type XVIII alpha 1 chain antibody.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western blot: 1/500-1/1000.
  Immunohistochemistry on Paraffin Sections: 1/50-1/200.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 300-350 of Human COL18A1.
• Specificity: This antibody detects endogenous levels of Collagen type XVIII alpha 1 chain (region surrounding Glu1322).
• Formulation: Phosphate buffered saline (PBS), pH 7.2.
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.05% Sodium azide
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography using epitope-specific immunogen (> 95% pure by SDS-PAGE)
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: ~ 179 kDa
• Gene Name: Homo sapiens collagen type XVIII alpha 1 (COL18A1), transcript variant 1
• Database Link:
  Entrez Gene 12822 MouseEntrez Gene 80781 Human
  UniProt ID P39060
• Background: The extensive family of COL gene products (collagens) is composed of several chain types, including fibril-forming interstitial collagens (types I, II, III and V) and basement membrane collagens (type IV), each type containing multiple isoforms. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function.
• Synonyms: COL18A1, Endostatin, KNO1