SGPL1 Rabbit Polyclonal Antibody

CAT#: AP05168PU-N

SGPL1 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis using S1P lyase 1 antibody at a dilution of 1:400 on MDBK cell lysate using mouse anti-rabbit HRP secondary antibody at 1:75,000.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western Blot: 1/400.
  Positive Control: Madin-Darby Bovine Kidney (MDBK) cell lysate.
• Reactivities: Bovine, Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide derived from the sphingosine 1-phosphate lyase 1 protein.
• Specificity: This antibody recognizes Sphingosine 1-Phosphate Lyase 1.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified IgG fraction
  Preservative: 0.08% Sodium Azide
• Concentration: lot specific
• Purification: Antigen Immunoaffiinity Chromatography
• Conjugation: Unconjugated
• Storage: Upon receipt, store undiluted (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: sphingosine-1-phosphate lyase 1
• Database Link:
  Entrez Gene 20397 MouseEntrez Gene 286896 RatEntrez Gene 8879 Human
  UniProt ID O95470
• Background: Sphingosine-1-phosphate lyase cleaves phosphorylated sphingoid bases, such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis. The catalytic activity of sphingosine 1-phosphate lyase converts sphingosine 1-phosphate to phosphoethanolamine and palmitaldehyde using Pyridoxal phosphate as a co-factor. Sphingosine 1-phosphate lyase is a type III membrane protein found in the endoplasmic reticulum. Sphingosine 1-phosphate lyase is found primarily in the liver and kidney. Sphingosine 1-phosphate lyase belongs to the group II decarboxylase family.
• Synonyms: SP-lyase 1, SPL 1, Sphingosine-1-phosphate aldolase, Sphingosine-1-phosphate lyase 1, KIAA1252

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Sphingolipid metabolism