Myeloperoxidase (MPO) Rabbit Polyclonal Antibody

CAT#: AP02121SU-S

Myeloperoxidase (MPO) rabbit polyclonal antibody, Serum

Size: 10 ug 100 ug


USD 126.00

2 Weeks*

Size
    • 10 ug

Product Images

Specifications

Product Data
Applications ELISA, IHC
Recommended Dilution ELISA.
Immunohistochemistry on Paraffin Sections.
Reactivities Human
Host Rabbit
Clonality Polyclonal
Immunogen Human Myeloperoxidase
Specificity This antibody detects Myeloperoxidase (MPO).
Formulation TRIS, pH 7.4
State: Serum
State: Lyophilized purified Serum
Reconstitution Method Restore in aqua bidest to 1 mg/ml.
Purification Protein G Chromatography
Conjugation Unconjugated
Storage Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month 
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name myeloperoxidase
Background Myeloperoxidase is a hemoprotein that is abundantly expressed in neutrophils and secreted during their activation. Native Myeloperoxidase is represented as a covalently bound tetrameric complex of two glycosylated alpha chains (MW 59 - 64 kDa) and two unglycosylated beta chains (MW 14 kDa) with total MW 150 kDa and theoretical pI 9.2. Traditionally Myeloperoxidase was considered as a main target of anti-neutrophil cytoplasm antibodies (ANCA), the serological markers for certain systemic vasculities e.g. periarteriitis nodosa, microscopic polyarteriitis and pulmonary eosinophilic granulomatosis (Churg-Strauss syndrome). Low to moderate anti-Myeloperoxidase autoantibody levels are also reported in rheumatoid arthritis. Recently it was shown that Myeloperoxidase participates in the initiation and progression of cardiovascular disease. It possesses potent proinflammatory properties and may contribute directly to tissue injury. Now Myeloperoxidase is under consideration as one of the most promising cardiac markers.
Synonyms MPO
Reference Data

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.