TSG6 (TNFAIP6) Rabbit Polyclonal Antibody

CAT#: AP01235PU-N

TSG6 (TNFAIP6) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of TSG-6 antibody in extracts from Jurkat cells.

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  Western blot (WB) analysis of TSG-6 antibody in extracts from MCF7 cells.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ELISA: 1/1000-1/5000.
  Western Blot: 1/500-1/1000.
  Immunofluorescence: 1/50-1/200.
  Immunohistochemistry on Paraffin Sections: 1/50-1/200.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to the N-terminal of Human TSG-6.
• Specificity: This antibody detects endogenous levels of TSG-6 protein. (region surrounding Val37)
• Formulation: PBS, pH~7.2 with 50% glycerol
  State: Aff - Purified
  State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE).
  Preservative: 15 mM Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.
• Predicted Protein Size: ~32 kDa
• Gene Name: TNF alpha induced protein 6
• Database Link:
  Entrez Gene 7130 Human
  UniProt ID P98066
• Background: TSG6 is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is involved in extracellular matrix stability and cell migration. This protein forms a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhances the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. The expression of this gene can be induced by tumor necrosis factor alpha and interleukin-1. The expression can also be induced by mechanical stimuli in vascular smooth muscle cells, and is correlated with proteoglycan synthesis and aggregation.
• Synonyms: TSG6, TSG-6