CD11c (ITGAX) Mouse Monoclonal Antibody [Clone ID: HC1/1]

CAT#: AM50207PU-S

CD11c (ITGAX) mouse monoclonal antibody, clone HC1/1, Purified

Product Images

FCM staining of Human PBMCs using CD11c Antibody (Clone HC1/1).

Specifications

Product Data

• Clone Name: HC1/1
• Applications: FC, IF, IHC, IP
• Recommended Dilution: ELISA: Use BSA free Antibody for coating.
  Functional Studies: Use Antibody without BSA and Azide.
  Flow Cytometry: 0.5-1 μg/million cells.
  Immunofluorescence: 0.5-1 μg/ml.
  Immunoprecipitation: 0.5-1 μg/500 μg protein lysate.
  Immunohistochemistry on Frozen Sections: 0.5-1.0 μg/ml for 30 minutes at RT.
  Positive Control: Human dendritic cells. Human lymph nodes and tonsils.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human monocytic U937 phorbol ester-treated cells.
• Specificity: CD11c, also known as Integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a type I transmembrane protein found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst; expressed in hairy cell leukemias, acute non-lymphocytic leukemias, and some B-cell chronic lymphocytic leukemias.
  Cellular Localization: Cell surface.
• Formulation: 10mM PBS
  State: Purified
  State: Liquid purified IgG fraction from Bioreactor Concentrate
  Stabilizer: 0.05% BSA
  Preservative: 0.05% Sodium Azide
• Concentration: lot specific
• Purification: Protein A/G Chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 145 kDa
• Gene Name: integrin subunit alpha X
• Database Link:
  Entrez Gene 3687 Human
  UniProt ID P20702
• Synonyms: ITGAX, Integrin alpha-X, Leu M5