T Cell Receptor (TCR) gamma/delta Mouse Monoclonal Antibody [Clone ID: 11F2]
CAT#: AM33019PU-N
T Cell Receptor (TCR) gamma/delta mouse monoclonal antibody, clone 11F2, Purified
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Specifications
Product Data | |
Clone Name | 11F2 |
Applications | ELISA, FC, IHC, IP |
Recommended Dilution | ELISA. Immunoprecipitation. Flow cytometry. Immunohistochemistry on Frozen sections. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Derived by fusion of SP2/0-Ag14 mouse myeloma cells with spleen cells from a Balb/C mice immunized with protein A-Sepharose/anti-CD3 antigen complex. |
Specificity | This Antibody clone 11F2 recognizes all molecular forms of the gamma/delta T-cell receptor (TCR) desribed so far. |
Formulation | PBS State: Purified State: Liquid purified IgG fraction Preservative: 0.09% Sodium Azide |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Background | Two types of T cell antigen receptors (TCRs) are now known, the α/β, and the γ/δ heterodimer, which are expressed at the cell surface in association with the CD3 molecular complex. TCR-γ can occur in either disulphide-linked or non-disulphide-linked forms. The γ/δ-TCR is present on a minor subset of T- lymphocytes in peripheral blood, thymus, spleen, and lymph nodes. In man and mouse, only a small part of the T-lymphocytes of the peripheral blood (<5%) is γ/δ. γ/δ T-lymphocytes may complement α/β T-cells in terms of antigenic specificities, functional capabilities, or sites of action within the body. |
Synonyms | TCRG, TCRD, T-Cell Receptor gamma, T-Cell Receptor delta, T-Cell Receptor gamma delta |
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