IL2 Receptor alpha (IL2RA) Mouse Monoclonal Antibody [Clone ID: B-G3]

CAT#: AM31171AF-N

IL2 Receptor alpha (IL2RA) mouse monoclonal antibody, clone B-G3, Azide Free

Product Images

A typical staining pattern with the B-G3 monoclonal antibody of PHA activated lymphocytes

Specifications

Product Data

• Clone Name: B-G3
• Applications: FC
• Recommended Dilution: Flow Cytometry.
  No effect on Mixed Lymphocyte Culture.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: PHA activated T cells
• Specificity: Recognises both soluble and membrane bound Interleukin 2 Receptor a chain (IL-2 Ra), a 55 kDa protein.
• Formulation: Phosphate-buffered saline.
  Sterile-filtered through 0.22 µm.
  Carrier and preservative free
  State: Azide Free
  State: Liquid purfied Ig fraction
• Concentration: lot specific
• Purification: Ion exchange chromatography
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C.
• Stability: Shelf life: one year from despatch.
• Gene Name: interleukin 2 receptor subunit alpha
• Database Link:
  Entrez Gene 3559 Human
  UniProt ID P01589
• Background: Genetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
• Synonyms: Interleukin-2 receptor alpha chain, IL-2 receptor alpha subunit, IL-2-RA, IL2-RA, p55, TAC antigen

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Jak-STAT signaling pathway