CD300E Mouse Monoclonal Antibody [Clone ID: UP-H2]

CAT#: AM26758PU-N

CD300E mouse monoclonal antibody, clone UP-H2, Purified

Specifications

Product Data

• Clone Name: UP-H2
• Applications: FC, FN, IP, WB
• Recommended Dilution: Flow cytometry.
  Immunoprecipitation.
  Western blot.
  Functional application: stimulation.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: CD300e-HA-transfected cells
• Specificity: This antibody recognizes CD300e / IREM-2, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells.
• Formulation: Phosphate buffered saline (PBS)
  State: Purified
  State: Liquid Ig fraction
  Preservative: 15 mM sodium azide, approx. pH 7.4
• Concentration: lot specific
• Purification: Protein-A affinity chromatography (> 95% pure by SDS-PAGE)
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C.
  DO NOT FREEZE!
  
• Stability: Shelf life: one year from despatch.
• Gene Name: CD300e molecule
• Database Link:
  Entrez Gene 342510 Human
  UniProt ID Q496F6
• Background: CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers.
• Synonyms: CLM-2, CD300LE, CLM2, IREM2, CMRF35-A5