C3 Mouse Monoclonal Antibody [Clone ID: 2B10B9B2]

CAT#: AM26369LE-N

C3 mouse monoclonal antibody, clone 2B10B9B2, Low Endotoxin

Specifications

Product Data

• Clone Name: 2B10B9B2
• Applications: ELISA, WB
• Recommended Dilution: Immunoassays.
  Western blot:
  The typical starting working dilution is 1:50.
  Not useful for immunoprecipitation.
• Reactivities: Rat
• Host: Mouse
• Isotype: IgM
• Clonality: Monoclonal
• Specificity:

  The monoclonal antibody 2B10B9B2 reacts with an epitope on C3b. The antibody reacts both with intact C3 and C3b.

• Formulation: State: Low Endotoxin
  Preservative: 0.02% sodium azide
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store at 2 - 8 °C.
  
• Stability: Shelf life: one year from despatch.
• Gene Name: complement component 3
• Database Link:
  Entrez Gene 24232 Rat
  UniProt ID P01026
• Background: The complement factor C3 consists of an alpha- and a beta-chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical and mannose binding lectin activation pathways lead to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to formation of the alpha-chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues including renal epithelial cells and hepatocytes.
• Synonyms: CPAMD1, Complement component 3