Klra6 Mouse Monoclonal Antibody [Clone ID: HBF-719]
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Specifications
Product Data | |
Clone Name | HBF-719 |
Applications | FC |
Recommended Dilution | Flow Cytometry. (Ref.1,3) |
Reactivities | Mouse |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | CHO cells transfected with the B6 allele of Ly49F. (Ref.1) |
Specificity | This antibody HBF-719 reacts with the B6 allele of Ly49F. It stains ~ 11% of NK1.1+CD3- splenocytes, and 3.5% (2.5 month old) to 10.0% (11 month old) of CD8+ spleen cells from C57BL/6 mice. (Ref.1) |
Formulation | PBS containing no preservatives. State: Low Endotoxin State: Liquid purified Ig fraction. |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted (In aliquots) at-20°C. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | killer cell lectin-like receptor, subfamily A, member 6 |
Database Link | |
Background | Ly49F is a member of the lectin like homodimeric Ly49 family of cell surface receptors. (Ref.1) Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells, while allowing them to attack infected or transformed cells in which class I molecules have been down regulated. (Ref.2) These inhibitory receptors are also expressed on a subpopulation of mouse CD8+ T cells. |
Synonyms | Ly-49f, Ly49-f, Ly49F |
Reference Data |
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