Hexokinase 1 (HK1) Mouse Monoclonal Antibody [Clone ID: 7A7]

CAT#: AM06493SU-N

Hexokinase 1 (HK1) mouse monoclonal antibody, clone 7A7, Ascites


USD 486.00

2 Weeks*

Size
    • 100 ul

Product Images

Specifications

Product Data
Clone Name 7A7
Applications ELISA, IF, IHC, WB
Recommended Dilution Western Blot: 1/500 - 1/2000.
Immunohistochemistry on paraffin sections: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: 1/10000.
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Purified recombinant fragment of human HK1 expressed in E. Coli.
Specificity This antibody reacts to HK1.
Formulation State: Ascites
State: Ascitic fluid containing 0.03% sodium azide.
Conjugation Unconjugated
Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Stability Shelf life: one year from despatch.

Predicted Protein Size 102 kDa
Gene Name hexokinase 1
Background The hexokinases utilize Mg-ATP as a phosphoryl donor to catalyze the first step of intracellular glucose metabolism, the conversion of glucose to glucose- 6-phosphate. Four hexokinase isoenzymes have been identified, including hexokinase I (HXK I), hexokinase II (HXK II), hexokinase III (HXK III) and hexokinase IV (HXK IV, also designated glucokinase or GCK). Hexokinases I-III each contain an N-terminal cluster of hydrophobic amino acids. Glucokinase lacks the N-terminal hydrophobic cluster. The hydrophobic cluster is thought to be necessary for membrane binding. This is substantiated by the finding that glucokinase has lower affinity for glucose than do the other hexokinases. HK I has been shown to be expressed in brain, kidney and heart tissues as well as in hepatoma cell lines.
Synonyms HK1, Hexokinase type I, Brain form hexokinase
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.