KLHL25 Mouse Monoclonal Antibody [Clone ID: 1B7]

CAT#: AM06471SU-N

KLHL25 mouse monoclonal antibody, clone 1B7, Ascites

Product Images

Western blot analysis using KLHL25 antibody Cat.-No AM06471SU-N against KLHL25 (AA: 2-230)-hIgGFc transfected HEK293 cell.

Specifications

Product Data

• Clone Name: 1B7
• Applications: ELISA, WB
• Recommended Dilution: ELISA: 1/10000.
  Western Blot: 1/500 - 1/2000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of Human KLHL25 expressed in E. Coli
• Specificity: Recognizes KLHL25
• Formulation: State: Ascites
  State: Ascitic fluid containing 0.03% Sodium Azide.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 65 kDa
• Database Link:
  Entrez Gene 64410 Human
  UniProt ID Q9H0H3
• Background: KLHL25 (ectoderm-neural cortex protein 2, ENC2) is a cytoplasmic protein that contains six Kelch regions and a single BTB (POZ) domain. KLHL25 is highly homologus to another Kelch-like protein, ENC1, and it is believed to operate in a manner similar to other Kelch-domain containing proteins. Kelch-domain repeat containing proteins often act as modifiers of Actin fibers. Expressed early in embryogenesis, ENC1 helps to mediate neuronal process formation. It also appears to have a role in neural crest cell differentiation. KLHL25 likely functions as a substrate specific adapter for protein ubiquitinating complexes. KLHL25 is expressed in most tissues with highest expression in brain and liver.
• Synonyms: KLHL25, ENC2, Ectoderm-neural cortex protein 2, ENC-2