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OriGene Antibody in recent publications
Comparison of the dose–response relationship of radiation-induced apoptosis in the hippocampal dentate gyrus and intestinal crypt of adult mice Radiat Prot Dosimetry, Mar 2012; 148: 492 - 497. [LGR5 ]

Tracking protein aggregation and mislocalization in cells with flow cytometry Nature Methods doi:10.1038/nmeth.1930 [HSPA1A]

Histone deacetylase inhibitors prevent the degradation and restore the activity of glucocerebrosidase in Gaucher disease PNAS, Dec 2011; 108: 21200 - 21205. [anti-DDK antibody]

Novel p65 Binding Glucocorticoid-induced Leucine Zipper Peptide Suppresses Experimental Autoimmune Encephalomyelitis J. Biol. Chem., Dec 2011; 286: 44799 - 44810. [anti-DDK]

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Toll-like receptor signaling pathway
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High Quality Primary Antibodies from OriGene

antibody

OriGene offers a broad selection of monoclonal and polyclonal antibodies to human proteins for various applications, including WB, IHC, IF/ICC, Flow and more.

Search primary antibodies – type gene symbol, protein name, accession number or keyword below:

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Browse antibodies based on alphabetical listing:

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Made against authentic protein antigens.
Recombinant protein detection.

Conjugates and substrates.
TrueMAB™ joint-development.


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To advance proteomic studies demands high quality antibodies for the detection of native epitopes of endogenous proteins. OriGene has developed TrueMAB™ monoclonal antibodies using authentic human proteins as antigens to advance the sensitivity and specificity of immunoassays. (superior qualities compared to peptide-derived antibodies)

TrueMAB™ antibodies were generated using recombinant human proteins as antigens (most of them are full length proteins expressed in human cell lines) that were affinity purified under native condition to preserve the protein conformations. The commonly available commercial antibodies were generated using short peptides. The peptide antigens are inadequate to mimic the protein conformations due to the lack of three-dimensional structures. In particular, peptide-derived antibodies cannot recognize conformational epitopes which are abundant on the surfaces of native proteins.

In comparison to peptide-derived antibodies, TrueMAB™ antibodies provide high sensitivity and specificity for the recognition of native epitopes appeared on the protein conformational structures. They are great tools for immunoassays that are sensitive to proteins’ conformations, such as immunofluorescence, immunoprecipitation, immunohistochemistry, flow cytometry, ELISA, antibody arrays and more

We are adding new TrueMAB™ antibodies against human proteins to our product list every month. For further questions, please send emails to antibody@origene.com or contact our technical supports

TrueMAB™ Antibody Flyer

* Peptide sequence of the DDK-tag (Flag®): N-DYKDDDDK-C. Flag® is a trademark of Sigma-Aldrich.