OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-ZYX antibodies

Anti-ZYX Antibody EPR4302

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA311113
  • Rabbit Monoclonal antibody against Zyxin (ZYX)
100ul 325 3-7 Days
Add to Shopping Cart
spacer
WB(1)
IHC(1)
IF(1)
spacer
Also for ZYX (NM_001010972)
cDNA Clone shRNA/siRNA Primer Pair Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Zyxin was used as an immunogen.
Clone NameEPR4302 IsotypeIgG
Species ReactivityMouse, Human (Does not react with: Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:10000 - 1:50000; IP: 1:10 - 1:100; IHC-P: 1:250 - 1:500; FC: 1:100 - 1:500; ICC/IF: 1:100 - 1:250
Predicted MW Explanation 61 kDa
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Does not react with Rat

Reference Data

Target NameHomo sapiens zyxin (ZYX), transcript variant 2
Alternative NameESP-2; HED-2
Database LinkNP_001010972
Entrez Gene 7791 Human
Entrez Gene 22793 Mouse
FunctionFocal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assembly. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways, while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles.
Related Pathway Focal adhesion

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Zyxin antibody [EPR4302]; All lanes : Anti-Zyxin antibody [EPR4302] at 1/10000 dilution.Lane 1 : HeLa lysate.Lane 2 : MCF7 lysate.Lane 3 : C2C12 lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 61 kDa.Observed band size : 82 kDa .
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Zyxin antibody [EPR4302]; Immunohistochemical analysis of Zyxin in paraffin embedded Human kidney tissue, using TA311113 at a 1/250 dilution.
IF Image
Immunocytochemistry/ Immunofluorescence - Zyxin antibody [EPR4302]; Immunofluorescent staining of Zyxin in HeLa cells, using TA311113 at a 1/100 dilution.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title