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Home Antibody All anti-ZNF536 antibodies

Anti-ZNF536 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA306881 Rabbit Polyclonal ZNF536 Antibody 100ug $325 3-7 Days
LC415091 ZNF536 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenZNF536 antibody was raised against a 16 amino acid peptide from near the amino terminus of human ZNF536.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/ml, IHC: 5 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens zinc finger protein 536 (ZNF536)
Alternative NameKIAA0390
Database LinkNP_055532
Entrez Gene 9745 Human
FunctionZNF536 is a recently identified zinc-finger protein that is expressed primarily in the developing nervous system and the cerebral cortex, hippocampus, and hypothalamus. ZNF536 possess ten zinc fingers and interacts with CtBP1, a corepressor for gene transcription. It is most closely related to transcriptional repressor ZNF219. Overexpression of ZNF536 in embryonic stem cells dramatically reduced the mRNA levels of neuronal marker genes such as Pax6, MAP2, and b-tubulin III following retinoic acid (RA)-induced differentiation, while depletion of ZNF536 via RNAi resulted in elevated mRNA levels of these genes, indicating its role in inhibiting neuronal cell differentiation. Overexpression of RA receptor a rescues the inhibitory role of ZNF536, suggesting that ZNF536 might inhibit RA response element-mediated transcriptional activity.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of ZNF536 in human brain tissue lysate with ZNF536 antibody at 1 ug/mL.
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Immunohistochemistry of ZNF536 in human brain tissue with ZNF536 antibody at 5 ug/mL.
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Immunofluorescence of ZNF536 in human brain tissue with ZNF536 antibody at 20 ug/mL.
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