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Home Antibody All anti-ZNF521 antibodies

Anti-ZNF521 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA319089 Rabbit polyclonal anti-ZNF521 antibody (NT) 100ug $379 2 Weeks
LC402451 ZNF521 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IF(1)

OriGene Data

ImmunogenZNF521 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human ZNF521.
Clone Name IsotypeRabbit IgG1
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsWB: 1ug/ml, ICC: 2.5ug/ml, ELISA
Buffer100 µg (1 mg/ml) in 1X PBS containing 1 mg/ml BSA, 50% glycerol and less than 0.02% sodium azide, pH 7.4.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens zinc finger protein 521 (ZNF521)
Alternative NameEHZF; Evi3
Database LinkNP_056276
Entrez Gene 25925 Human
FunctionThe zinc finger protein 521 (ZNF521) is a transcription factor containing an N-terminal transcriptional repressor motif and 30 zinc finger domains. It plays a role in both erythroid cell and osteoblast differentiation during development, inhibiting the activities of early B-cell factor 1 (EBF1) in erythroid cells and Runx2 in osteoblast precursors. ZFP521 binds to both Runx2 and histone deacetylase 3 (HDAC3), promotes their association and antagonizes Runx2 transcriptional activity in a HDAC3-dependent manner, thereby regulating osteoblast differentiation, skeletal development, and bone homeostasis.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of ZNF521 in HeLa cell lysate with ZNF521 antibody at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide.
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Immunocytochemistry of HeLa cells with ZNF521 antibody at 2.5ug/ml.
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