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Home Antibody All anti-ZNF521 antibodies

Anti-ZNF521 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319089
  • Rabbit polyclonal anti-ZNF521 antibody (NT)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402451) , 20ug Explanation
100ug 379 In Stock
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WB(1)
IF(1)
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Also for ZNF521 (NM_015461)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenZNF521 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human ZNF521.
Clone Name IsotypeRabbit IgG1
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsWB: 1ug/ml, ICC: 2.5ug/ml, ELISA
Buffer100 µg (1 mg/ml) in 1X PBS containing 1 mg/ml BSA, 50% glycerol and less than 0.02% sodium azide, pH 7.4.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens zinc finger protein 521 (ZNF521)
Alternative NameEHZF; Evi3
Database LinkNP_056276
Entrez Gene 25925 Human
FunctionThe zinc finger protein 521 (ZNF521) is a transcription factor containing an N-terminal transcriptional repressor motif and 30 zinc finger domains. It plays a role in both erythroid cell and osteoblast differentiation during development, inhibiting the activities of early B-cell factor 1 (EBF1) in erythroid cells and Runx2 in osteoblast precursors. ZFP521 binds to both Runx2 and histone deacetylase 3 (HDAC3), promotes their association and antagonizes Runx2 transcriptional activity in a HDAC3-dependent manner, thereby regulating osteoblast differentiation, skeletal development, and bone homeostasis.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of ZNF521 in HeLa cell lysate with ZNF521 antibody at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide.
IF Image
Immunocytochemistry of HeLa cells with ZNF521 antibody at 2.5ug/ml.

 

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