Home Antibody All anti-ZBED3 antibodies
Also for ZBED3 (NM_032367)
|ZBED3 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human ZBED3.|
||ELISA, WB: 1 ug/ml, ICC: 20 ug/ml
|PBS containing 0.02% sodium azide.|
|Affinity chromatography purified via peptide column
|Homo sapiens zinc finger, BED-type containing 3 (ZBED3)|
Entrez Gene 84327 Human
|Axin is a key modulator of the Wnt/beta-catenin pathway and acts as a scaffold protein in phosphorylating and degrading cytoplasmic beta-catenin. ZBED3, a member of the Zinc finger BED-type domain containing superfamily, has been recently identified as an Axin-interacting protein and has been suggested to modulate the Wnt/beta-catenin signaling pathway. RNA interference (RNAi) experiments targeting ZBED3 RNA attenuated Wnt-induced beta-catenin accumulation, lymphoid enhancer binding factor-1-dependent luciferase reporter activity, and Wnt gene expression. Despite its predicted molecular weight, ZBED3 often migrates at a higher position in SDS-PAGE. This antibody is predicted to have no cross-reactivity to ZBED1 or ZBED2.|
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Western blot analysis of ZBED3 in human lung tissue lysate with ZBED3 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
Immunocytochemistry of ZBED3 in A549 cells with ZBED3 antibody at 20 ug/mL.