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Home Antibody All anti-ZBED3 antibodies

Anti-ZBED3 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA306755 Rabbit Polyclonal ZBED3 Antibody 100ug $325 3-7 Days
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WB(1)
IF(1)

OriGene Data

ImmunogenZBED3 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human ZBED3.
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 ug/ml, ICC: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens zinc finger, BED-type containing 3 (ZBED3)
Alternative NameMGC15435
Database LinkNP_115743
Entrez Gene 84327 Human
FunctionAxin is a key modulator of the Wnt/beta-catenin pathway and acts as a scaffold protein in phosphorylating and degrading cytoplasmic beta-catenin. ZBED3, a member of the Zinc finger BED-type domain containing superfamily, has been recently identified as an Axin-interacting protein and has been suggested to modulate the Wnt/beta-catenin signaling pathway. RNA interference (RNAi) experiments targeting ZBED3 RNA attenuated Wnt-induced beta-catenin accumulation, lymphoid enhancer binding factor-1-dependent luciferase reporter activity, and Wnt gene expression. Despite its predicted molecular weight, ZBED3 often migrates at a higher position in SDS-PAGE. This antibody is predicted to have no cross-reactivity to ZBED1 or ZBED2.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of ZBED3 in human lung tissue lysate with ZBED3 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunocytochemistry of ZBED3 in A549 cells with ZBED3 antibody at 20 ug/mL.
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