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Home Antibody All anti-ZBED1 antibodies

Anti-ZBED1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306754
  • Rabbit Polyclonal ZBED1 Antibody
100ug $325 3-7 Days
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WB(1)
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Also for ZBED1 (NM_001171135)
cDNA Clone shRNA/siRNA Primer Pair Protein Antibody

OriGene Data

ImmunogenZBED1 antibody was raised against a 15 amino acid peptide from near the center of human ZBED1.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens zinc finger, BED-type containing 1 (ZBED1), transcript variant 3
Alternative NameALTE; DREF; hDREF; TRAMP
Database LinkNP_001164606
FunctionZBED1, also known as DREF, is the human homolog of the Drosophila protein DREF, a transcriptional regulatory factor required for expression of genes involved in DNA replication and cell proliferation. RNA interference (RNAi) experiments targeting ZBED1 RNA resulted in the inhibition of S phase entry and reduction of histone H1 mRNA in HeLa cells, suggesting that ZBED1 also plays a role in cell proliferation in human cells. At least 22 ribosomal proteins (RPs) possess ZBED1 binding sites in their promoters; anti-ZBED1 RNAi also resulted in decreased RP gene expression. Immunoprecipitation analyses have shown that ZBED1 self-associates in vivo via a carboxyl-terminal hATC domain, and this self-association is required for nuclear localization and DNA binding. This antibody is predicted to have no cross-reactivity to ZBED2 or ZBED3.
Related Pathway

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WB Image
Western blot analysis of ZBED1 in A549 cell lysate with ZBED1 antibody at 1 µg/ml.

 

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