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Home Antibody All anti-ZAP70 antibodies

Anti-ZAP70 Antibody YE291

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303738
  • Rabbit monoclonal antibody against ZAP-70(YE291)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC421504) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(5)
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Also for ZAP70 (NM_001079)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in C-terminus of human ZAP-70 was used as immunogen.
Clone NameYE291 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:500; IHC-P: Use at an assay dependent dilution; ICC: 1:100 - 1:250; FC: 1:80; IP: 1:50
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens zeta-chain (TCR) associated protein kinase 70kDa (ZAP70), transcript variant 1
Alternative NameSRK; STCD; STD; TZK; ZAP-70
Database LinkNP_001070
Entrez Gene 7535 Human
FunctionThis gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq].
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - ZAP70 antibody [YE291]; Anti-ZAP70 antibody [YE291] at 1/500 dilution + Jurkat cell lysate.Predicted band size : 70 kDa.Observed band size : 70 kDa.
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - ZAP70 antibody [YE291]; Ab32429, at a 1/100 dilution, staining ZAP70 in paraffin embedded human lymph node tissue by immunohistochemistry.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-ZAP70 antibody [YE291](TA303738); TA303738 showing positive staining in Normal tonsil tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-ZAP70 antibody [YE291](TA303738); TA303738 showing negative staining in Normal liver tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-ZAP70 antibody [YE291](TA303738); TA303738 showing negative staining in Normal heart tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-ZAP70 antibody [YE291](TA303738); TA303738 showing negative staining in Normal kidney tissue.

 

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