OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-YWHAE antibodies

Anti-YWHAE Antibody

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA321781
  • Anti-YWHAE Rabbit Polyclonal Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402021) , 20ug Explanation
100ul 325 2-3 Weeks
Add to Shopping Cart
spacer
WB(1)
IHC(1)
spacer
Also for YWHAE (NM_006761)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSynthetic peptide corresponding to a region derived from 70-84 amino acids of Human tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration2.6mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsELISA: 1:2000-10000, WB: 1:1000-5000, IHC: 1:50-200
Predicted MW Explanation 29kDa
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon (YWHAE), transcript variant 1
Alternative Name14-3-3E; HEL2; KCIP-1; MDCR; MDS
Database LinkNP_006752
Entrez Gene 7531 Human
Entrez Gene 22627 Mouse
Entrez Gene 29753 Rat
FunctionThis gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals; and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases; RAF1 and IRS1 proteins; suggesting its role in diverse biochemical activities related to signal transduction; such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants; one protein-coding and the other non-protein-coding; have been found for this gene.?
Related PathwayDruggable Genome Cell cycleOocyte meiosisNeurotrophin signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Predicted band size: 29 kDa . Positive control: Human brain malignant glioma and laryngocarcinoma tissue . Recommended dilution: 1/1000-5000. (Gel: 12%SDS-PAGE Lane1:Human brain malignant glioma tissue lysate Lane2:Human laryngocarcinoma tissue lysate Lysates: 40 ug per lane Primary antibody: 1/1300 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 30 seconds)
IHC Image
Predicted cell location: Cytoplasm. Positive control: Human colon cancer tissue. Recommended dilution: 1/50-200 The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using YWHAE antibody at dilution 1/60, on the right is treated with the synthetic peptide. (Original magnification:x200)

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title