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Home Antibody All anti-YWHAE antibodies

Anti-YWHAE Antibody

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Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA321779 Anti-YWHAE Rabbit Polyclonal Antibody 100ul $325 In Stock
LC402021 YWHAE HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for YWHAE (NM_006761)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFusion protein corresponding to C terminal 254 amino acids of Human Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.8mg/ml
Guaranteed Application * Suggested DilutionsELISA: 1:500-10000, WB: 1:500-2000, IHC: 1:25-150
Predicted MW Explanation 29kDa
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon (YWHAE), transcript variant 1
Alternative Name14-3-3E; HEL2; KCIP-1; MDCR; MDS
Database LinkNP_006752
Entrez Gene 7531 Human
Entrez Gene 22627 Mouse
Entrez Gene 29753 Rat
FunctionThis gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals; and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases; RAF1 and IRS1 proteins; suggesting its role in diverse biochemical activities related to signal transduction; such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants; one protein-coding and the other non-protein-coding; have been found for this gene.
Related PathwayDruggable Genome Cell cycleOocyte meiosisNeurotrophin signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

 

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