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Home Antibody All anti-YWHAE antibodies

Anti-YWHAE Antibody EPR3919

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307144
  • Rabbit monoclonal antibody against 14-3-3E(clone EPR3919)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC402021) , 20ug
100ul $325 In Stock
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WB(1)
IF(1)
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Also for YWHAE (NM_006761)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human 14-3-3E was used as an immunogen.
Clone NameEPR3919 IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IF Suggested DilutionsWB: 1:1000 - 1:10000; FC: 1:10 - 1:100; ICC/IF: 1:100 - 1:250
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for ICC or IP.

Reference Data

Target NameHomo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon (YWHAE), transcript variant 1
Alternative Name14-3-3E; HEL2; KCIP-1; MDCR; MDS
Database LinkNP_006752
FunctionThe 14-3-3 epsilon protein (14-3-3E) is one of seven isoforms in the 14-3-3 protein family, which consists of acidic proteins expressed at high levels in neurons of the central nervous system (1). It is an adaptor protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. 14-3-3E binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif (2). It also interacts with both insulin-like growth factor I receptor (IGFIR) and insulin receptor substrate I (IRS-1), suggesting its role in the regulation of insulin sensitivity (3). 14-3-3E has also been implicated in the pathogenesis of small cell lung cancer (4).
Related Pathway
Cell cycle

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WB Image
Western blot - 14-3-3 epsilon antibody [EPR3919]; All lanes : Anti-14-3-3 epsilon antibody [EPR3919].Lane 1 : Fetal brain lysate.Lane 2 : SW480 cell lysate.Lane 3 : NIH/3T3 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 29 kDa.
IF Image
Immunocytochemistry/ Immunofluorescence - 14-3-3 epsilon antibody [EPR3919]; TA307144, at a 1/100 dilution, staining 14-3-3 epsilon in HeLa cells by Immunofluorescence.

 

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