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Home Antibody All anti-YWHAB antibodies

Anti-YWHAB Antibody Y62


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA300356 Rabbit Monoclonal Antibody against YWHAB (Clone Y62) 100ul $325 In Stock
LC403387 YWHAB HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for YWHAB (NM_139323)
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OriGene Data

ImmunogenA synthetic peptide corresponding to C-terminal residues of human 14-3-3 ß/a was used as immunogen. Predicted to cross-react with rat and bovine, based on sequence homology.
Clone NameY62 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000; IHC-P: Use at an assay dependent dilution; ICC: 1:500; IP: 1:40; FC: 1:40
Predicted MW Explanation 30 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%

Reference Data

Target NameHomo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta (YWHAB), transcript variant 2
Alternative NameGW128; HEL-S-1; HS1; KCIP-1; YWHAA
Database LinkNP_647539
Entrez Gene 7529 Human
Entrez Gene 54401 Mouse
Entrez Gene 56011 Rat
FunctionThe 14-3-3 proteins are a family of proteins involved in the regulation of apoptosis, mitogenic signaling and cell-cycle checkpoints (1). The 14-3-3 proteins are thought to be key regulators of signal transduction events mediated through their binding to serine-phosphorylated proteins (2,3). Through binding Bad, 14-3-3 prevents apoptosis by sequestering Bad to the cytosol (3).
Related PathwayDruggable Genome Cell cycleOocyte meiosisNeurotrophin signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - 14-3-3 alpha + beta antibody [Y62]; Anti-14-3-3 alpha + beta antibody [Y62] at 1/1000 dilution + Hela cell lysate.Predicted band size : 30 kDa.Observed band size : 28 kDa .

IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - 14-3-3 alpha + beta antibody [Y62]; Ab32560, at a 1/500 dilution, staining 14-3-3 alpha + beta in paraffin embedded human breast tissue by Immunohistochemistry.


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