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Home Antibody All anti-YPEL3 antibodies

Anti-YPEL3 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA320038
  • Rabbit Polyclonal YPEL3 Antibody
100ug 325 In Stock
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WB(1)
IF(1)

OriGene Data

ImmunogenYPEL3 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human YPEL3.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1 mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 ug/ml, ICC: 2.5 ug/ml, IF: 2.5 ug/ml
BufferYPEL3 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification YPEL3 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens yippee-like 3 (Drosophila) (YPEL3), transcript variant 1
Alternative NameMGC10500
Database LinkNP_113665
FunctionYPEL3 Antibody: YPEL3 (yippee-like 3) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL3 is a p53-regulated gene whose expression is induced by DNA damage and in turn induces cellular senescence. It appears to function as a tumor suppressor as it is downregulated in colon and breast tumors.
Related Pathway

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WB Image
Western blot analysis of YPEL3 in A-20 cell lysate with YPEL3 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide
IF Image
Immunofluorescence of YPEL3 in A20 cells with YPEL3 antibody at 5 ug/mL.

 

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