Home Antibody All anti-XRCC5 antibodies
Also for XRCC5 (NM_021141)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 315 and 563 of Ku80 (XRCC5)|
|WB, IHC, IF
||WB:1:500-1:3000; IHC:1:100; IF:1:100-1:200;
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
|Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) (XRCC5)|
|KARP-1; KARP1; KU80; Ku86; KUB2; NFIV|
|The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq]|
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Sample (30ug whole cell lysate) A:MOLT4 (anti-XRCC5 antibody diluted at 1:1000)
Immunohistochemical analysis of paraffin-embedded Cal27 Xenograft, using Ku80 (XRCC5)(anti-XRCC5 antibody) antibody at 1:100 dilution.
Immunofluorescence analysis of methanol-fixed HeLa, using Ku80 (XRCC5)(anti-XRCC5 antibody) antibody at 1:200 dilution.