Home Antibody All anti-XRCC4 antibodies
Also for XRCC4 (NM_022406)
|Synthetic peptide corresponding to a region within amino acids 216 and 309 of XRCC4 (Uniprot ID#Q13426)|
|Human (Predicted: Mouse, Rat, Bovine)
|WB, IHC, IF
||ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Mouse (86%), Rat (86%), Bovine (93%)
|Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 4 (XRCC4), transcript variant 2|
|DNA repair protein XRCC4; X-ray repair cross complementing protein 4; X-ray repair, complementing defective, repair in Chinese hamster; X-ray repair complementing defective repair in Chinese hamster cells 4|
Entrez Gene 7518 Human
Entrez Gene 108138 Mouse
Entrez Gene 309995 Rat
|The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants. [provided by RefSeq]|
|Druggable Genome Non-homologous end-joining|
* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
Sample (30 ug of whole cell lysate). A: Jurkat. B: K562. C: HL-60. 10% SDS PAGE. TA308834 diluted at 1:1000.
XRCC4 antibody detects XRCC4 protein at nucleus on HBL435 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded HBL435 xenograft. XRCC4 antibody (TA308834) dilution: 1:500.
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using XRCC4(TA308834) antibody at 1:200 dilution.