Home Antibody All anti-XRCC3 antibodies
Also for XRCC3 (NM_001100119)
|Recombinant fragment corresponding to a region within amino acids 202 and 346 of XRCC3 (Uniprot ID#O43542)|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 3 (XRCC3), transcript variant 1|
Entrez Gene 7517 Human
|This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq]|
|Druggable Genome Homologous recombination|
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XRCC3 antibody detects XRCC3 protein by western blot analysis. A. 30 ug 293T whole cell lysate/extract. B. 30 ug whole cell lysate/extract of DDDDK-human XRCC3-transfected 293T cells. 10 % SDS-PAGE. XRCC3 antibody (TA308545) dilution: 1:1000
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using XRCC3(TA308545) antibody at 1:200 dilution.