A synthetic peptide corresponding to residues near the C-terminus of human Exportin 4 was used as an immunogen.
Buffer
Store at -20 C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Exportin 4 is a novel member of the importin-beta family that was shown to transport the eukaryotic translation initiation factor 5A (eIF-5A) to the cytoplasm via recognition of a complex nuclear export signal (1,2). Exportin 4 was identified as an interaction partner of Sox2 in mouse ES cells and neural progenitors and show that it also serves as a bona fide nuclear import receptor for Sox2 and SRY (3).
Related Pathway
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