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Home Antibody All anti-WNT3 antibodies

Anti-WNT3 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302636
  • Goat Polyclonal Antibody against WNT3
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC403082) , 20ug
100ug 325 3-7 Days
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WB(1)
IHC(1)

OriGene Data

ImmunogenPeptide with sequence CGRGHNTRTEKRKEK, from the internal region of the protein sequence according to NP_110380.1.
Clone Name IsotypeGoat IgG
Species ReactivityHuman, Mouse Concentration0.5 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsELISA: 1:16,000; WB: 1-3 ug/ml; IHC: 2-4 ug/ml
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Note In paraffin embedded Human Breast shows cytoplasm staining in some luminal epithelial cells

Reference Data

Target NameHomo sapiens wingless-type MMTV integration site family, member 3 (WNT3)
Alternative NameINT4
Database LinkNP_110380
FunctionThe WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region. [provided by RefSeq].
Related Pathway
Hedgehog signaling pathway
Melanogenesis
Wnt Signaling Pathway

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WB Image
TA302636 (1µg/ml) staining of lysate of cell line HEK293 (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
IHC Image
TA302636 (2µg/ml) staining of paraffin embedded Human Breast. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.

 

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