Home Antibody All anti-WNT10A antibodies
Also for WNT10A (NM_025216)
|Recombinant fragment corresponding to a region within amino acids 47 and 271 of WNT10A (Uniprot ID#Q9GZT5)|
|Human (Predicted: Mouse, Rat, Bovine)
||Lot dependent; please refer to CoA along with shipment
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Mouse (96%), Rat (97%), Bovine (96%)
|Homo sapiens wingless-type MMTV integration site family, member 10A (WNT10A)|
|OODD; SSPS; STHAG4|
Entrez Gene 80326 Human
Entrez Gene 22409 Mouse
Entrez Gene 316527 Rat
|The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt's lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene overexpression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway. This gene and the WNT6 gene are clustered in the chromosome 2q35 region. [provided by RefSeq]|
|Secreted ProteinTransmembrane Wnt signaling pathwayHedgehog signaling pathwayMelanogenesisPathways in cancerBasal cell carcinoma|
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Sample (30 ug of whole cell lysate). A: Raji. 10% SDS PAGE. TA308635 diluted at 1:1000.
WNT10A antibody [N1C1-2] detects WNT10A protein at cytoplasm by immunofluorescent analysis. Sample: SKNSH cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: WNT10A protein stained by WNT10A antibody [N1C1-2] (TA308635) diluted at 1:500. Blue