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Home Antibody All anti-WNT10A antibodies

Anti-WNT10A Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306591
  • Rabbit Polyclonal Wnt10a Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC403062) , 20ug
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for WNT10A (NM_025216)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenWnt10a antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human Wnt10a.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens wingless-type MMTV integration site family, member 10A (WNT10A)
Alternative NameOODD; SSPS; STHAG4
Database LinkNP_079492
FunctionWnt10a is a member of the Wnt family, a gene family that encodes secreted signaling proteins that play crucial roles in normal development such as regulation of cell fate and patterning during embryogenesis as well as neoplastic transformation. Elevated levels of Wnt10a have been detected in several human tumors and cancer cell lines including colorectal cancer and chronic lymphocytic leukemia and it has been suggested that uncontrolled Wnt signaling may contribute to the defect in apoptosis that characterizes these malignancies. Recently, a mutation in Wnt10a was found to be associated with odonto-onycho-dermal dysplasia, an autosomal recessive ectodermal dysplasia. Despite the high homology of Wnt10a to Wnt10b, this Wnt10a antibody will not cross-react with Wnt10b.
Related Pathway
Hedgehog signaling pathway
Melanogenesis
Wnt Signaling Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of Wnt10a in RAW264.7 cell lysate with Wnt10a antibody at (A) 1 and (B) 2 ug/ml.
IHC Image
Immunohistochemistry of Wnt10a in human skeletal muscle tissue cells with Wnt10a antibody at 10 ug/ml.

 

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