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Home Antibody All anti-WNT1 antibodies

Anti-WNT1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319125
  • Rabbit polyclonal anti-Wnt-1 antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401668) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
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Also for WNT1 (NM_005430)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenE. coli expressed human Wnt-1
Clone Name IsotypeRabbit IgG
Species ReactivityHuman Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5-4 ug/ml
Buffer100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification Affinity purified

Reference Data

Target NameHomo sapiens wingless-type MMTV integration site family, member 1 (WNT1)
Alternative NameBMND16; INT1; OI15
Database LinkNP_005421
Entrez Gene 7471 Human
FunctionWnt-1 is a secreted protein that signals through the Frizzled family of cell surface receptors and is required for normal embryonic development. Wnt-1 activation induces a complex signaling cascade that ultimately leads to the increased expression of over fifty genes. An important component of Wnt-1 signaling is the stabilization, and resulting accumulation, of the intracellular signaling protein, beta-catenine. Wnt signaling induces and maintains the transformed phenotype and, in certain embryonic cell lines, supports self renewal in the absence of significant differentiation. Elevated levels of Wnt proteins are associated with tumorigenesis and are present in numerous human breast cancers. Mature human Wnt-1 is a glycosylated protein containing 343 amino acid residues.
Related PathwayStem cell relevant signaling - Wnt Signaling pathwaySecreted ProteinES Cell Differentiation/IPSTransmembraneAdult stem cellsCancer stem cellsDruggable Genome Wnt signaling pathwayHedgehog signaling pathwayMelanogenesisPathways in cancerBasal cell carcinoma

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis using recombinant human Wnt-1. Lane 1: 5 ng, Lane2: 10 ng, Lane 3: 50 ng.

 

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