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Anti-WIPI2 Antibody Polyclonal
Also for WIPI2 (NM_016003)
|Rabbit polyclonal WIPI2 antibody was raised against a 17 amino acid peptide near the amino terminus of human WIPI2.|
||ELISA, WB: 1 - 2 ug/ml
|WIPI2 Antibody is supplied in PBS containing 0.02% sodium azide.|
|WIPI2 Antibody is affinity chromatography purified via peptide column.
|Homo sapiens WD repeat domain, phosphoinositide interacting 2 (WIPI2), transcript variant 2|
|ATG18B; Atg21; CGI-50; WIPI-2|
Entrez Gene 26100 Human
Entrez Gene 288498 Rat
|WIPI2 Antibody: WD repeat proteins play a role in many essential biologic functions, regulating the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. WIPI2, also known as ATG18B or ATG21, is a human homolog to yeast ATG18 and contains three WD repeats and has a 7-bladed propeller structure with a conserved motif that facilitates its interaction with other proteins. It is recruited to early autophagosomal structures along with Atg16L and ULK1 and is required for the formation of LC3-positive autophagosomes. Along with the highly related WIPI1, WIPI2 is found at the plasma membrane in addition to autophagosomal membranes.|
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Western blot analysis of WIPI2 in human testis tissue lysate with WIPI2 antibody at 1 ug/mL