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Home Antibody All anti-WASF1 antibodies

Anti-WASF1 Antibody S91-36


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA326418 Mouse monoclonal WAVE1/SCAR Antibody 100µg $325 3-7 Days
LC418341 WASF1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenSynthetic peptide amino acids 477-498 of human Wave1/Wasp family1,
Clone NameS91-36 IsotypeIgG1
Species ReactivityHuman, Mouse, Rat Concentration1mg/mL
Guaranteed Application * Suggested DilutionsWB: 1ug/ml, IHC: 0.1-1ug/ml, IF: 1-10ug/ml
BufferPBS pH7.4, 50% glycerol, 0.09% sodium azide
Purification Protein G Purified
Note Detects ~75kDa.

Reference Data

Target NameHomo sapiens WAS protein family member 1 (WASF1), transcript variant 1
Alternative NameSCAR1; WAVE; WAVE1
Database LinkNP_003922
Entrez Gene 8936 Human
Entrez Gene 83767 Mouse
Entrez Gene 294568 Rat
FunctionThe Wiskott-Aldrich syndrome protein (WASP) family plays essential roles in the regulation of actin polymerization. There are five WASP family members: Wasp, N-WASP, Wave1 (WASP family verprolin-homologous protein 1), WAVE2 and WAVE3. The Wasp family proteins share a conserved C-terminal region called the verprolin homology, cofilin homology and acidic domain . The Wave/Scar family of prtoteins mediates signals to actin assembly by direct activation of the Arp2/3 complex. These proteins have been characterized as major regulators of lamellipodia formation downstream of Rac activation, and as members of large protein complexes. IT has been found that all three Scar/Wave isoforms behave similarily and are likely to participate in the same kinds of protein complexes .
Related PathwayDruggable Genome Adherens junctionFc gamma R-mediated phagocytosisRegulation of actin cytoskeleton

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