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Home Antibody All anti-VEGFA antibodies
UltraMAB

Anti-VEGFA GAT Antibody Polyclonal

Generated by Genomic Immunization

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA590655
  • Rabbit Polyclonal VEGF Antibody
50ug 325 3-7 Days
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Also for VEGFA (NM_003376)
cDNA Clone shRNA/siRNA Primer Pair Protein Antibody

OriGene Data

ImmunogenDNA immunization. This antibody was made against a protein fragment from the N Terminus Region
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration1.04 mg/ml
Guaranteed Application * Suggested DilutionsWB: 1:5000-1:20000; ELISA: 1:100-1:2000
Buffer20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Purification The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

Target NameHomo sapiens vascular endothelial growth factor A (VEGFA), transcript variant 2
Alternative NameMVCD1; VEGF; VPF
Database LinkNP_003367
Entrez Gene 7422 Human
FunctionThis gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms.
Related Pathway
Cytokine-cytokine receptor interaction
Focal Adhesion
Hemostasis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

 

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